MicroRNA-155 Implication in M1 Polarization and the Impact in Inflammatory Diseases
Identifieur interne : 000277 ( Main/Exploration ); précédent : 000276; suivant : 000278MicroRNA-155 Implication in M1 Polarization and the Impact in Inflammatory Diseases
Auteurs : Sergiu Pasca [Roumanie] ; Ancuta Jurj [Roumanie] ; Bobe Petrushev [Roumanie] ; Ciprian Tomuleasa [Roumanie] ; Daniela Matei [Roumanie]Source :
- Frontiers in Immunology [ 1664-3224 ] ; 2020.
Abstract
Macrophages are known to have an impact in cytokine signaling in the myriad of organs in which they reside and are classically known to be either pro-inflammatory (M1), anti-inflammatory (M2). Different classes of signaling molecules influence these states, of which, microRNAs represent key modulators. These are short RNA species approximately 21 to 23 nucleotides long that generally act by binding to the 3′ untranslated region of mRNAs, regulating their translation, and, thus, the quantity of protein they encode. From these species, microRNA-155 was observed to be of great importance for M1 polarization. Because of it’s major implication in M1 polarization microRNA-155 was shown to be implicated in different inflammatory diseases. To name a few, microRNA-155 was shown to be modified in patients with asthma and to correlate with asthma symptoms in mouse model; it has been shown to modulate the activity of foam cells and influence the dimensions of the atherosclerotic plaque and it has also been shown to be of crucial influence in transducing the signal of LPS in septic shock. Because of this, the current review aims to offer an overview of the role of microRNA-155 in M1 polarization, the implication that this poses for the pathophysiology of inflammatory diseases and the potential therapeutic possibilities that this knowledge might bring. Currently, microRNA-155 has been used in clinical trials as a marker of inflammation, but the question remains if it’s inhibition will be useful in inflammatory diseases, as other products might have a better cost/benefit ratio.
Url:
DOI: 10.3389/fimmu.2020.00625
PubMed: NONE
PubMed Central: 7174664
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000F54
- to stream Pmc, to step Curation: 000F54
- to stream Pmc, to step Checkpoint: 000189
- to stream Ncbi, to step Merge: 002D82
- to stream Ncbi, to step Curation: 002D82
- to stream Ncbi, to step Checkpoint: 002D82
- to stream Main, to step Merge: 000277
- to stream Main, to step Curation: 000277
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">MicroRNA-155 Implication in M1 Polarization and the Impact in Inflammatory Diseases</title><author><name sortKey="Pasca, Sergiu" sort="Pasca, Sergiu" uniqKey="Pasca S" first="Sergiu" last="Pasca">Sergiu Pasca</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Hematology, Iuliu Hatieganu University of Medicine and Pharmacy</institution>,<addr-line>Cluj-Napoca</addr-line>,<country>Romania</country></nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Jurj, Ancuta" sort="Jurj, Ancuta" uniqKey="Jurj A" first="Ancuta" last="Jurj">Ancuta Jurj</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Research Center for Functional Genomics, Biomedicine and Translational Medicine, Iuliu Hatieganu University of Medicine and Pharmacy</institution>,<addr-line>Cluj-Napoca</addr-line>,<country>Romania</country></nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Petrushev, Bobe" sort="Petrushev, Bobe" uniqKey="Petrushev B" first="Bobe" last="Petrushev">Bobe Petrushev</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>“Octavian Fodor” Institute of Gastroenterology and Hepatology</institution>,<addr-line>Cluj-Napoca</addr-line>,<country>Romania</country></nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Tomuleasa, Ciprian" sort="Tomuleasa, Ciprian" uniqKey="Tomuleasa C" first="Ciprian" last="Tomuleasa">Ciprian Tomuleasa</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Hematology, Iuliu Hatieganu University of Medicine and Pharmacy</institution>,<addr-line>Cluj-Napoca</addr-line>,<country>Romania</country></nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff4"><institution>The Oncology Institute Prof. Dr. Ion Chiricuta</institution>,<addr-line>Cluj-Napoca</addr-line>,<country>Romania</country></nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Matei, Daniela" sort="Matei, Daniela" uniqKey="Matei D" first="Daniela" last="Matei">Daniela Matei</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>“Octavian Fodor” Institute of Gastroenterology and Hepatology</institution>,<addr-line>Cluj-Napoca</addr-line>,<country>Romania</country></nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Department of Gastroenterology, Iuliu Hatieganu University of Medicine and Pharmacy</institution>,<addr-line>Cluj-Napoca</addr-line>,<country>Romania</country></nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmc">7174664</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174664</idno><idno type="RBID">PMC:7174664</idno><idno type="doi">10.3389/fimmu.2020.00625</idno><idno type="pmid">NONE</idno><date when="2020">2020</date><idno type="wicri:Area/Pmc/Corpus">000F54</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000F54</idno><idno type="wicri:Area/Pmc/Curation">000F54</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000F54</idno><idno type="wicri:Area/Pmc/Checkpoint">000189</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000189</idno><idno type="wicri:Area/Ncbi/Merge">002D82</idno><idno type="wicri:Area/Ncbi/Curation">002D82</idno><idno type="wicri:Area/Ncbi/Checkpoint">002D82</idno><idno type="wicri:Area/Main/Merge">000277</idno><idno type="wicri:Area/Main/Curation">000277</idno><idno type="wicri:Area/Main/Exploration">000277</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">MicroRNA-155 Implication in M1 Polarization and the Impact in Inflammatory Diseases</title><author><name sortKey="Pasca, Sergiu" sort="Pasca, Sergiu" uniqKey="Pasca S" first="Sergiu" last="Pasca">Sergiu Pasca</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Hematology, Iuliu Hatieganu University of Medicine and Pharmacy</institution>,<addr-line>Cluj-Napoca</addr-line>,<country>Romania</country></nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Jurj, Ancuta" sort="Jurj, Ancuta" uniqKey="Jurj A" first="Ancuta" last="Jurj">Ancuta Jurj</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Research Center for Functional Genomics, Biomedicine and Translational Medicine, Iuliu Hatieganu University of Medicine and Pharmacy</institution>,<addr-line>Cluj-Napoca</addr-line>,<country>Romania</country></nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Petrushev, Bobe" sort="Petrushev, Bobe" uniqKey="Petrushev B" first="Bobe" last="Petrushev">Bobe Petrushev</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>“Octavian Fodor” Institute of Gastroenterology and Hepatology</institution>,<addr-line>Cluj-Napoca</addr-line>,<country>Romania</country></nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Tomuleasa, Ciprian" sort="Tomuleasa, Ciprian" uniqKey="Tomuleasa C" first="Ciprian" last="Tomuleasa">Ciprian Tomuleasa</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Hematology, Iuliu Hatieganu University of Medicine and Pharmacy</institution>,<addr-line>Cluj-Napoca</addr-line>,<country>Romania</country></nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff4"><institution>The Oncology Institute Prof. Dr. Ion Chiricuta</institution>,<addr-line>Cluj-Napoca</addr-line>,<country>Romania</country></nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Matei, Daniela" sort="Matei, Daniela" uniqKey="Matei D" first="Daniela" last="Matei">Daniela Matei</name><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>“Octavian Fodor” Institute of Gastroenterology and Hepatology</institution>,<addr-line>Cluj-Napoca</addr-line>,<country>Romania</country></nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Department of Gastroenterology, Iuliu Hatieganu University of Medicine and Pharmacy</institution>,<addr-line>Cluj-Napoca</addr-line>,<country>Romania</country></nlm:aff><country xml:lang="fr">Roumanie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Frontiers in Immunology</title><idno type="eISSN">1664-3224</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Macrophages are known to have an impact in cytokine signaling in the myriad of organs in which they reside and are classically known to be either pro-inflammatory (M1), anti-inflammatory (M2). Different classes of signaling molecules influence these states, of which, microRNAs represent key modulators. These are short RNA species approximately 21 to 23 nucleotides long that generally act by binding to the 3′ untranslated region of mRNAs, regulating their translation, and, thus, the quantity of protein they encode. From these species, microRNA-155 was observed to be of great importance for M1 polarization. Because of it’s major implication in M1 polarization microRNA-155 was shown to be implicated in different inflammatory diseases. To name a few, microRNA-155 was shown to be modified in patients with asthma and to correlate with asthma symptoms in mouse model; it has been shown to modulate the activity of foam cells and influence the dimensions of the atherosclerotic plaque and it has also been shown to be of crucial influence in transducing the signal of LPS in septic shock. Because of this, the current review aims to offer an overview of the role of microRNA-155 in M1 polarization, the implication that this poses for the pathophysiology of inflammatory diseases and the potential therapeutic possibilities that this knowledge might bring. Currently, microRNA-155 has been used in clinical trials as a marker of inflammation, but the question remains if it’s inhibition will be useful in inflammatory diseases, as other products might have a better cost/benefit ratio.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Lawrence, T" uniqKey="Lawrence T">T Lawrence</name></author><author><name sortKey="Natoli, G" uniqKey="Natoli G">G. Natoli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="O Rien, J" uniqKey="O Rien J">J O’Brien</name></author><author><name sortKey="Hayder, H" uniqKey="Hayder H">H Hayder</name></author><author><name sortKey="Zayed, Y" uniqKey="Zayed Y">Y Zayed</name></author><author><name sortKey="Peng, C" uniqKey="Peng C">C. Peng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Olson, Mc" uniqKey="Olson M">MC Olson</name></author><author><name sortKey="Scott, Ew" uniqKey="Scott E">EW Scott</name></author><author><name sortKey="Hack, Aa" uniqKey="Hack A">AA Hack</name></author><author><name sortKey="Su, Gh" uniqKey="Su G">GH Su</name></author><author><name sortKey="Tenen, Dg" uniqKey="Tenen D">DG Tenen</name></author><author><name sortKey="Singh, H" uniqKey="Singh H">H Singh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nerlov, C" uniqKey="Nerlov C">C Nerlov</name></author><author><name sortKey="Graf, T" uniqKey="Graf T">T. Graf</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dekoter, Rp" uniqKey="Dekoter R">RP. DeKoter</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rosenbauer, F" uniqKey="Rosenbauer F">F Rosenbauer</name></author><author><name sortKey="Tenen, Dg" uniqKey="Tenen D">DG. Tenen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Darnell, J" uniqKey="Darnell J">J Darnell</name></author><author><name sortKey="Kerr, I" uniqKey="Kerr I">I Kerr</name></author><author><name sortKey="Stark, G" uniqKey="Stark G">G. Stark</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gordon, S" uniqKey="Gordon S">S Gordon</name></author><author><name sortKey="Taylor, Pr" uniqKey="Taylor P">PR. Taylor</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Park, C" uniqKey="Park C">C Park</name></author><author><name sortKey="Li, S" uniqKey="Li S">S Li</name></author><author><name sortKey="Cha, E" uniqKey="Cha E">E Cha</name></author><author><name sortKey="Schindler, C" uniqKey="Schindler C">C. Schindler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krausgruber, T" uniqKey="Krausgruber T">T Krausgruber</name></author><author><name sortKey="Blazek, K" uniqKey="Blazek K">K Blazek</name></author><author><name sortKey="Smallie, T" uniqKey="Smallie T">T Smallie</name></author><author><name sortKey="Alzabin, S" uniqKey="Alzabin S">S Alzabin</name></author><author><name sortKey="Lockstone, H" uniqKey="Lockstone H">H Lockstone</name></author><author><name sortKey="Sahgal, N" uniqKey="Sahgal N">N Sahgal</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Takaoka, A" uniqKey="Takaoka A">A Takaoka</name></author><author><name sortKey="Yanai, H" uniqKey="Yanai H">H Yanai</name></author><author><name sortKey="Kondo, S" uniqKey="Kondo S">S Kondo</name></author><author><name sortKey="Duncan, G" uniqKey="Duncan G">G Duncan</name></author><author><name sortKey="Negishi, H" uniqKey="Negishi H">H Negishi</name></author><author><name sortKey="Mizutani, T" uniqKey="Mizutani T">T Mizutani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mosser, Dm" uniqKey="Mosser D">DM Mosser</name></author><author><name sortKey="Edwards, Jp" uniqKey="Edwards J">JP. Edwards</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Takeda, K" uniqKey="Takeda K">K Takeda</name></author><author><name sortKey="Tanaka, T" uniqKey="Tanaka T">T Tanaka</name></author><author><name sortKey="Shi, W" uniqKey="Shi W">W Shi</name></author><author><name sortKey="Matsumoto, M" uniqKey="Matsumoto M">M Matsumoto</name></author><author><name sortKey="Minami, M" uniqKey="Minami M">M Minami</name></author><author><name sortKey="Kashiwamura, S" uniqKey="Kashiwamura S">S Kashiwamura</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Satoh, T" uniqKey="Satoh T">T Satoh</name></author><author><name sortKey="Takeuchi, O" uniqKey="Takeuchi O">O Takeuchi</name></author><author><name sortKey="Vandenbon, A" uniqKey="Vandenbon A">A Vandenbon</name></author><author><name sortKey="Yasuda, K" uniqKey="Yasuda K">K Yasuda</name></author><author><name sortKey="Tanaka, Y" uniqKey="Tanaka Y">Y Tanaka</name></author><author><name sortKey="Kumagai, Y" uniqKey="Kumagai Y">Y Kumagai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Szanto, A" uniqKey="Szanto A">A Szanto</name></author><author><name sortKey="Balint, Bl" uniqKey="Balint B">BL Balint</name></author><author><name sortKey="Nagy, Zs" uniqKey="Nagy Z">ZS Nagy</name></author><author><name sortKey="Barta, E" uniqKey="Barta E">E Barta</name></author><author><name sortKey="Dezso, B" uniqKey="Dezso B">B Dezso</name></author><author><name sortKey="Pap, A" uniqKey="Pap A">A Pap</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ricote, M" uniqKey="Ricote M">M Ricote</name></author><author><name sortKey="Li, Ac" uniqKey="Li A">AC Li</name></author><author><name sortKey="Willson, Tm" uniqKey="Willson T">TM Willson</name></author><author><name sortKey="Kelly, Cj" uniqKey="Kelly C">CJ Kelly</name></author><author><name sortKey="Glass, Ck" uniqKey="Glass C">CK. Glass</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pascual, G" uniqKey="Pascual G">G Pascual</name></author><author><name sortKey="Fong, Al" uniqKey="Fong A">AL Fong</name></author><author><name sortKey="Ogawa, S" uniqKey="Ogawa S">S Ogawa</name></author><author><name sortKey="Gamliel, A" uniqKey="Gamliel A">A Gamliel</name></author><author><name sortKey="Li, Ac" uniqKey="Li A">AC Li</name></author><author><name sortKey="Perissi, V" uniqKey="Perissi V">V Perissi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, N" uniqKey="Huang N">N Huang</name></author><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y Zhang</name></author><author><name sortKey="Chen, M" uniqKey="Chen M">M Chen</name></author><author><name sortKey="Jin, H" uniqKey="Jin H">H Jin</name></author><author><name sortKey="Nie, J" uniqKey="Nie J">J Nie</name></author><author><name sortKey="Luo, Y" uniqKey="Luo Y">Y Luo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="El Kasmi, Kc" uniqKey="El Kasmi K">KC El Kasmi</name></author><author><name sortKey="Qualls, Je" uniqKey="Qualls J">JE Qualls</name></author><author><name sortKey="Pesce, Jt" uniqKey="Pesce J">JT Pesce</name></author><author><name sortKey="Smith, Am" uniqKey="Smith A">AM Smith</name></author><author><name sortKey="Thompson, Rw" uniqKey="Thompson R">RW Thompson</name></author><author><name sortKey="Henao Tamayo, M" uniqKey="Henao Tamayo M">M Henao-Tamayo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ruffell, D" uniqKey="Ruffell D">D Ruffell</name></author><author><name sortKey="Mourkioti, F" uniqKey="Mourkioti F">F Mourkioti</name></author><author><name sortKey="Gambardella, A" uniqKey="Gambardella A">A Gambardella</name></author><author><name sortKey="Kirstetter, P" uniqKey="Kirstetter P">P Kirstetter</name></author><author><name sortKey="Lopez, Rg" uniqKey="Lopez R">RG Lopez</name></author><author><name sortKey="Rosenthal, N" uniqKey="Rosenthal N">N Rosenthal</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Friedman, Ad" uniqKey="Friedman A">AD. Friedman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gordon, S" uniqKey="Gordon S">S Gordon</name></author><author><name sortKey="Martinez, Fo" uniqKey="Martinez F">FO. Martinez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ohmori, Y" uniqKey="Ohmori Y">Y Ohmori</name></author><author><name sortKey="Hamilton, Ta" uniqKey="Hamilton T">TA. Hamilton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Santa, F" uniqKey="De Santa F">F De Santa</name></author><author><name sortKey="Narang, V" uniqKey="Narang V">V Narang</name></author><author><name sortKey="Yap, Zh" uniqKey="Yap Z">ZH Yap</name></author><author><name sortKey="Tusi, Bk" uniqKey="Tusi B">BK Tusi</name></author><author><name sortKey="Burgold, T" uniqKey="Burgold T">T Burgold</name></author><author><name sortKey="Austenaa, L" uniqKey="Austenaa L">L Austenaa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Foster, Sl" uniqKey="Foster S">SL Foster</name></author><author><name sortKey="Hargreaves, Dc" uniqKey="Hargreaves D">DC Hargreaves</name></author><author><name sortKey="Medzhitov, R" uniqKey="Medzhitov R">R. Medzhitov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mann, M" uniqKey="Mann M">M Mann</name></author><author><name sortKey="Mehta, A" uniqKey="Mehta A">A Mehta</name></author><author><name sortKey="Zhao, Jl" uniqKey="Zhao J">JL Zhao</name></author><author><name sortKey="Lee, K" uniqKey="Lee K">K Lee</name></author><author><name sortKey="Marinov, Gk" uniqKey="Marinov G">GK Marinov</name></author><author><name sortKey="Garcia Flores, Y" uniqKey="Garcia Flores Y">Y Garcia-Flores</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gebert, Lfr" uniqKey="Gebert L">LFR Gebert</name></author><author><name sortKey="Macrae, Ij" uniqKey="Macrae I">IJ. MacRae</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Treiber, T" uniqKey="Treiber T">T Treiber</name></author><author><name sortKey="Treiber, N" uniqKey="Treiber N">N Treiber</name></author><author><name sortKey="Meister, G" uniqKey="Meister G">G. Meister</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alivernini, S" uniqKey="Alivernini S">S Alivernini</name></author><author><name sortKey="Gremese, E" uniqKey="Gremese E">E Gremese</name></author><author><name sortKey="Mcsharry, C" uniqKey="Mcsharry C">C McSharry</name></author><author><name sortKey="Tolusso, B" uniqKey="Tolusso B">B Tolusso</name></author><author><name sortKey="Ferraccioli, G" uniqKey="Ferraccioli G">G Ferraccioli</name></author><author><name sortKey="Mcinnes, Ib" uniqKey="Mcinnes I">IB McInnes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Quinn, Sr" uniqKey="Quinn S">SR Quinn</name></author><author><name sortKey="Mangan, Ne" uniqKey="Mangan N">NE Mangan</name></author><author><name sortKey="Caffrey, Be" uniqKey="Caffrey B">BE Caffrey</name></author><author><name sortKey="Gantier, Mp" uniqKey="Gantier M">MP Gantier</name></author><author><name sortKey="Williams, Brg" uniqKey="Williams B">BRG Williams</name></author><author><name sortKey="Hertzog, Pj" uniqKey="Hertzog P">PJ Hertzog</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="O Onnell, Rm" uniqKey="O Onnell R">RM O’Connell</name></author><author><name sortKey="Taganov, Kd" uniqKey="Taganov K">KD Taganov</name></author><author><name sortKey="Boldin, Mp" uniqKey="Boldin M">MP Boldin</name></author><author><name sortKey="Cheng, G" uniqKey="Cheng G">G Cheng</name></author><author><name sortKey="Baltimore, D" uniqKey="Baltimore D">D. Baltimore</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kurowska Stolarska, M" uniqKey="Kurowska Stolarska M">M Kurowska-Stolarska</name></author><author><name sortKey="Hasoo, Mk" uniqKey="Hasoo M">MK Hasoo</name></author><author><name sortKey="Welsh, Dj" uniqKey="Welsh D">DJ Welsh</name></author><author><name sortKey="Stewart, L" uniqKey="Stewart L">L Stewart</name></author><author><name sortKey="Mcintyre, D" uniqKey="Mcintyre D">D McIntyre</name></author><author><name sortKey="Morton, Be" uniqKey="Morton B">BE Morton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bruning, U" uniqKey="Bruning U">U Bruning</name></author><author><name sortKey="Cerone, L" uniqKey="Cerone L">L Cerone</name></author><author><name sortKey="Neufeld, Z" uniqKey="Neufeld Z">Z Neufeld</name></author><author><name sortKey="Fitzpatrick, Sf" uniqKey="Fitzpatrick S">SF Fitzpatrick</name></author><author><name sortKey="Cheong, A" uniqKey="Cheong A">A Cheong</name></author><author><name sortKey="Scholz, Cc" uniqKey="Scholz C">CC Scholz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chinenov, Y" uniqKey="Chinenov Y">Y Chinenov</name></author><author><name sortKey="Coppo, M" uniqKey="Coppo M">M Coppo</name></author><author><name sortKey="Gupte, R" uniqKey="Gupte R">R Gupte</name></author><author><name sortKey="Sacta, Ma" uniqKey="Sacta M">MA Sacta</name></author><author><name sortKey="Rogatsky, I" uniqKey="Rogatsky I">I. Rogatsky</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zheng, Y" uniqKey="Zheng Y">Y Zheng</name></author><author><name sortKey="Xiong, S" uniqKey="Xiong S">S Xiong</name></author><author><name sortKey="Jiang, P" uniqKey="Jiang P">P Jiang</name></author><author><name sortKey="Liu, R" uniqKey="Liu R">R Liu</name></author><author><name sortKey="Liu, X" uniqKey="Liu X">X Liu</name></author><author><name sortKey="Qian, J" uniqKey="Qian J">J Qian</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Elton, Ts" uniqKey="Elton T">TS Elton</name></author><author><name sortKey="Selemon, H" uniqKey="Selemon H">H Selemon</name></author><author><name sortKey="Elton, Sm" uniqKey="Elton S">SM Elton</name></author><author><name sortKey="Parinandi, Nl" uniqKey="Parinandi N">NL. Parinandi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nazari Jahantigh, M" uniqKey="Nazari Jahantigh M">M Nazari-Jahantigh</name></author><author><name sortKey="Wei, Y" uniqKey="Wei Y">Y Wei</name></author><author><name sortKey="Noels, H" uniqKey="Noels H">H Noels</name></author><author><name sortKey="Akhtar, S" uniqKey="Akhtar S">S Akhtar</name></author><author><name sortKey="Zhou, Z" uniqKey="Zhou Z">Z Zhou</name></author><author><name sortKey="Koenen, Rr" uniqKey="Koenen R">RR Koenen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="O Onnell, Rm" uniqKey="O Onnell R">RM O’Connell</name></author><author><name sortKey="Chaudhuri, Aa" uniqKey="Chaudhuri A">AA Chaudhuri</name></author><author><name sortKey="Rao, Ds" uniqKey="Rao D">DS Rao</name></author><author><name sortKey="Baltimore, D" uniqKey="Baltimore D">D. Baltimore</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="An, H" uniqKey="An H">H An</name></author><author><name sortKey="Xu, H" uniqKey="Xu H">H Xu</name></author><author><name sortKey="Zhang, M" uniqKey="Zhang M">M Zhang</name></author><author><name sortKey="Zhou, J" uniqKey="Zhou J">J Zhou</name></author><author><name sortKey="Feng, T" uniqKey="Feng T">T Feng</name></author><author><name sortKey="Qian, C" uniqKey="Qian C">C Qian</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jing, W" uniqKey="Jing W">W Jing</name></author><author><name sortKey="Zhang, X" uniqKey="Zhang X">X Zhang</name></author><author><name sortKey="Sun, W" uniqKey="Sun W">W Sun</name></author><author><name sortKey="Hou, X" uniqKey="Hou X">X Hou</name></author><author><name sortKey="Yao, Z" uniqKey="Yao Z">Z Yao</name></author><author><name sortKey="Zhu, Y" uniqKey="Zhu Y">Y. Zhu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="He, M" uniqKey="He M">M He</name></author><author><name sortKey="Xu, Z" uniqKey="Xu Z">Z Xu</name></author><author><name sortKey="Ding, T" uniqKey="Ding T">T Ding</name></author><author><name sortKey="Kuang, D M" uniqKey="Kuang D">D-M Kuang</name></author><author><name sortKey="Zheng, L" uniqKey="Zheng L">L. Zheng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, H" uniqKey="Kim H">H. Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Martinez Nunez, Rt" uniqKey="Martinez Nunez R">RT Martinez-Nunez</name></author><author><name sortKey="Louafi, F" uniqKey="Louafi F">F Louafi</name></author><author><name sortKey="Sanchez Elsner, T" uniqKey="Sanchez Elsner T">T. Sanchez-Elsner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wahl, Sm" uniqKey="Wahl S">SM Wahl</name></author><author><name sortKey="Allen, Jb" uniqKey="Allen J">JB Allen</name></author><author><name sortKey="Costa, Gl" uniqKey="Costa G">GL Costa</name></author><author><name sortKey="Wong, Hl" uniqKey="Wong H">HL Wong</name></author><author><name sortKey="Dasch, Jr" uniqKey="Dasch J">JR. Dasch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Louafi, F" uniqKey="Louafi F">F Louafi</name></author><author><name sortKey="Martinez Nunez, Rt" uniqKey="Martinez Nunez R">RT Martinez-Nunez</name></author><author><name sortKey="Sanchez Elsner, T" uniqKey="Sanchez Elsner T">T. Sanchez-Elsner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Filipowicz, W" uniqKey="Filipowicz W">W Filipowicz</name></author><author><name sortKey="Bhattacharyya, Sn" uniqKey="Bhattacharyya S">SN Bhattacharyya</name></author><author><name sortKey="Sonenberg, N" uniqKey="Sonenberg N">N. Sonenberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bushati, N" uniqKey="Bushati N">N Bushati</name></author><author><name sortKey="Cohen, Sm" uniqKey="Cohen S">SM. Cohen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tarassishin, L" uniqKey="Tarassishin L">L Tarassishin</name></author><author><name sortKey="Loudig, O" uniqKey="Loudig O">O Loudig</name></author><author><name sortKey="Bauman, A" uniqKey="Bauman A">A Bauman</name></author><author><name sortKey="Shafit Zagardo, B" uniqKey="Shafit Zagardo B">B Shafit-Zagardo</name></author><author><name sortKey="Suh, H S" uniqKey="Suh H">H-S Suh</name></author><author><name sortKey="Lee, Sc" uniqKey="Lee S">SC. Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhou, H" uniqKey="Zhou H">H Zhou</name></author><author><name sortKey="Huang, X" uniqKey="Huang X">X Huang</name></author><author><name sortKey="Cui, H" uniqKey="Cui H">H Cui</name></author><author><name sortKey="Luo, X" uniqKey="Luo X">X Luo</name></author><author><name sortKey="Tang, Y" uniqKey="Tang Y">Y Tang</name></author><author><name sortKey="Chen, S" uniqKey="Chen S">S Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Feketea, G" uniqKey="Feketea G">G Feketea</name></author><author><name sortKey="Bocsan, Ci" uniqKey="Bocsan C">CI Bocsan</name></author><author><name sortKey="Popescu, C" uniqKey="Popescu C">C Popescu</name></author><author><name sortKey="Gaman, M" uniqKey="Gaman M">M Gaman</name></author><author><name sortKey="Stanciu, La" uniqKey="Stanciu L">LA Stanciu</name></author><author><name sortKey="Zdrenghea, Mt" uniqKey="Zdrenghea M">MT. Zdrenghea</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, H" uniqKey="Li H">H Li</name></author><author><name sortKey="Jiang, T" uniqKey="Jiang T">T Jiang</name></author><author><name sortKey="Li, M Q" uniqKey="Li M">M-Q Li</name></author><author><name sortKey="Zheng, X L" uniqKey="Zheng X">X-L Zheng</name></author><author><name sortKey="Zhao, G J" uniqKey="Zhao G">G-J. Zhao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Comer, Bs" uniqKey="Comer B">BS Comer</name></author><author><name sortKey="Camoretti Mercado, B" uniqKey="Camoretti Mercado B">B Camoretti-Mercado</name></author><author><name sortKey="Kogut, Pc" uniqKey="Kogut P">PC Kogut</name></author><author><name sortKey="Halayko, Aj" uniqKey="Halayko A">AJ Halayko</name></author><author><name sortKey="Solway, J" uniqKey="Solway J">J Solway</name></author><author><name sortKey="Gerthoffer, Wt" uniqKey="Gerthoffer W">WT. Gerthoffer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Suojalehto, H" uniqKey="Suojalehto H">H Suojalehto</name></author><author><name sortKey="Lindstrom, I" uniqKey="Lindstrom I">I Lindström</name></author><author><name sortKey="Majuri, M L" uniqKey="Majuri M">M-L Majuri</name></author><author><name sortKey="Mitts, C" uniqKey="Mitts C">C Mitts</name></author><author><name sortKey="Karjalainen, J" uniqKey="Karjalainen J">J Karjalainen</name></author><author><name sortKey="Wolff, H" uniqKey="Wolff H">H Wolff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pinkerton, M" uniqKey="Pinkerton M">M Pinkerton</name></author><author><name sortKey="Chinchilli, V" uniqKey="Chinchilli V">V Chinchilli</name></author><author><name sortKey="Banta, E" uniqKey="Banta E">E Banta</name></author><author><name sortKey="Craig, T" uniqKey="Craig T">T Craig</name></author><author><name sortKey="August, A" uniqKey="August A">A August</name></author><author><name sortKey="Bascom, R" uniqKey="Bascom R">R Bascom</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Malmh Ll, C" uniqKey="Malmh Ll C">C Malmhäll</name></author><author><name sortKey="Johansson, K" uniqKey="Johansson K">K Johansson</name></author><author><name sortKey="Winkler, C" uniqKey="Winkler C">C Winkler</name></author><author><name sortKey="Alawieh, S" uniqKey="Alawieh S">S Alawieh</name></author><author><name sortKey="Ekerljung, L" uniqKey="Ekerljung L">L Ekerljung</name></author><author><name sortKey="R Dinger, M" uniqKey="R Dinger M">M. Rådinger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Qiu, L" uniqKey="Qiu L">L Qiu</name></author><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y Zhang</name></author><author><name sortKey="Do, Dc" uniqKey="Do D">DC Do</name></author><author><name sortKey="Ke, X" uniqKey="Ke X">X Ke</name></author><author><name sortKey="Zhang, S" uniqKey="Zhang S">S Zhang</name></author><author><name sortKey="Lambert, K" uniqKey="Lambert K">K Lambert</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, H" uniqKey="Chen H">H Chen</name></author><author><name sortKey="Xu, X" uniqKey="Xu X">X Xu</name></author><author><name sortKey="Cheng, S" uniqKey="Cheng S">S Cheng</name></author><author><name sortKey="Xu, Y" uniqKey="Xu Y">Y Xu</name></author><author><name sortKey="Xuefei, Q" uniqKey="Xuefei Q">Q Xuefei</name></author><author><name sortKey="Cao, Y" uniqKey="Cao Y">Y Cao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Libby, P" uniqKey="Libby P">P Libby</name></author><author><name sortKey="Buring, Je" uniqKey="Buring J">JE Buring</name></author><author><name sortKey="Badimon, L" uniqKey="Badimon L">L Badimon</name></author><author><name sortKey="Hansson, Gk" uniqKey="Hansson G">GK Hansson</name></author><author><name sortKey="Deanfield, J" uniqKey="Deanfield J">J Deanfield</name></author><author><name sortKey="Bittencourt, Ms" uniqKey="Bittencourt M">MS Bittencourt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Du, F" uniqKey="Du F">F Du</name></author><author><name sortKey="Yu, F" uniqKey="Yu F">F Yu</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Hui, Y" uniqKey="Hui Y">Y Hui</name></author><author><name sortKey="Carnevale, K" uniqKey="Carnevale K">K Carnevale</name></author><author><name sortKey="Fu, M" uniqKey="Fu M">M Fu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, Y" uniqKey="Yang Y">Y Yang</name></author><author><name sortKey="Yang, L" uniqKey="Yang L">L Yang</name></author><author><name sortKey="Liang, X" uniqKey="Liang X">X Liang</name></author><author><name sortKey="Zhu, G" uniqKey="Zhu G">G. Zhu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ye, J" uniqKey="Ye J">J Ye</name></author><author><name sortKey="Guo, R" uniqKey="Guo R">R Guo</name></author><author><name sortKey="Shi, Y" uniqKey="Shi Y">Y Shi</name></author><author><name sortKey="Qi, F" uniqKey="Qi F">F Qi</name></author><author><name sortKey="Guo, C" uniqKey="Guo C">C Guo</name></author><author><name sortKey="Yang, L" uniqKey="Yang L">L. Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Donners, Mmpc" uniqKey="Donners M">MMPC Donners</name></author><author><name sortKey="Wolfs, Imj" uniqKey="Wolfs I">IMJ Wolfs</name></author><author><name sortKey="Stoger, Lj" uniqKey="Stoger L">LJ Stöger</name></author><author><name sortKey="Van Der Vorst, Epc" uniqKey="Van Der Vorst E">EPC van der Vorst</name></author><author><name sortKey="Pottgens, Cch" uniqKey="Pottgens C">CCH Pöttgens</name></author><author><name sortKey="Heymans, S" uniqKey="Heymans S">S Heymans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aletaha, D" uniqKey="Aletaha D">D Aletaha</name></author><author><name sortKey="Smolen, Js" uniqKey="Smolen J">JS. Smolen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stanczyk, J" uniqKey="Stanczyk J">J Stanczyk</name></author><author><name sortKey="Pedrioli, Dml" uniqKey="Pedrioli D">DML Pedrioli</name></author><author><name sortKey="Brentano, F" uniqKey="Brentano F">F Brentano</name></author><author><name sortKey="Sanchez Pernaute, O" uniqKey="Sanchez Pernaute O">O Sanchez-Pernaute</name></author><author><name sortKey="Kolling, C" uniqKey="Kolling C">C Kolling</name></author><author><name sortKey="Gay, Re" uniqKey="Gay R">RE Gay</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Murata, K" uniqKey="Murata K">K Murata</name></author><author><name sortKey="Yoshitomi, H" uniqKey="Yoshitomi H">H Yoshitomi</name></author><author><name sortKey="Tanida, S" uniqKey="Tanida S">S Tanida</name></author><author><name sortKey="Ishikawa, M" uniqKey="Ishikawa M">M Ishikawa</name></author><author><name sortKey="Nishitani, K" uniqKey="Nishitani K">K Nishitani</name></author><author><name sortKey="Ito, H" uniqKey="Ito H">H Ito</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Elmesmari, A" uniqKey="Elmesmari A">A Elmesmari</name></author><author><name sortKey="Fraser, Ar" uniqKey="Fraser A">AR Fraser</name></author><author><name sortKey="Wood, C" uniqKey="Wood C">C Wood</name></author><author><name sortKey="Gilchrist, D" uniqKey="Gilchrist D">D Gilchrist</name></author><author><name sortKey="Vaughan, D" uniqKey="Vaughan D">D Vaughan</name></author><author><name sortKey="Stewart, L" uniqKey="Stewart L">L Stewart</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pauley, Km" uniqKey="Pauley K">KM Pauley</name></author><author><name sortKey="Satoh, M" uniqKey="Satoh M">M Satoh</name></author><author><name sortKey="Chan, Al" uniqKey="Chan A">AL Chan</name></author><author><name sortKey="Bubb, Mr" uniqKey="Bubb M">MR Bubb</name></author><author><name sortKey="Reeves, Wh" uniqKey="Reeves W">WH Reeves</name></author><author><name sortKey="Chan, Ek" uniqKey="Chan E">EK. Chan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wentowski, C" uniqKey="Wentowski C">C Wentowski</name></author><author><name sortKey="Mewada, N" uniqKey="Mewada N">N Mewada</name></author><author><name sortKey="Nielsen, Nd" uniqKey="Nielsen N">ND. Nielsen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Taganov, Kd" uniqKey="Taganov K">KD Taganov</name></author><author><name sortKey="Boldin, Mp" uniqKey="Boldin M">MP Boldin</name></author><author><name sortKey="Chang, K J" uniqKey="Chang K">K-J Chang</name></author><author><name sortKey="Baltimore, D" uniqKey="Baltimore D">D. Baltimore</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tili, E" uniqKey="Tili E">E Tili</name></author><author><name sortKey="Michaille, J J" uniqKey="Michaille J">J-J Michaille</name></author><author><name sortKey="Cimino, A" uniqKey="Cimino A">A Cimino</name></author><author><name sortKey="Costinean, S" uniqKey="Costinean S">S Costinean</name></author><author><name sortKey="Dumitru, Cd" uniqKey="Dumitru C">CD Dumitru</name></author><author><name sortKey="Adair, B" uniqKey="Adair B">B Adair</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dobson, R" uniqKey="Dobson R">R Dobson</name></author><author><name sortKey="Giovannoni, G" uniqKey="Giovannoni G">G. Giovannoni</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Moore, Cs" uniqKey="Moore C">CS Moore</name></author><author><name sortKey="Rao, Vts" uniqKey="Rao V">VTS Rao</name></author><author><name sortKey="Durafourt, Ba" uniqKey="Durafourt B">BA Durafourt</name></author><author><name sortKey="Bedell, Bj" uniqKey="Bedell B">BJ Bedell</name></author><author><name sortKey="Ludwin, Sk" uniqKey="Ludwin S">SK Ludwin</name></author><author><name sortKey="Bar Or, A" uniqKey="Bar Or A">A Bar-Or</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Junker, A" uniqKey="Junker A">A Junker</name></author><author><name sortKey="Krumbholz, M" uniqKey="Krumbholz M">M Krumbholz</name></author><author><name sortKey="Eisele, S" uniqKey="Eisele S">S Eisele</name></author><author><name sortKey="Mohan, H" uniqKey="Mohan H">H Mohan</name></author><author><name sortKey="Augstein, F" uniqKey="Augstein F">F Augstein</name></author><author><name sortKey="Bittner, R" uniqKey="Bittner R">R Bittner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Digby Bell, Jl" uniqKey="Digby Bell J">JL Digby-Bell</name></author><author><name sortKey="Atreya, R" uniqKey="Atreya R">R Atreya</name></author><author><name sortKey="Monteleone, G" uniqKey="Monteleone G">G Monteleone</name></author><author><name sortKey="Powell, N" uniqKey="Powell N">N. Powell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lu, Z J" uniqKey="Lu Z">Z-J Lu</name></author><author><name sortKey="Wu, J J" uniqKey="Wu J">J-J Wu</name></author><author><name sortKey="Jiang, W L" uniqKey="Jiang W">W-L Jiang</name></author><author><name sortKey="Xiao, J H" uniqKey="Xiao J">J-H Xiao</name></author><author><name sortKey="Tao, K Z" uniqKey="Tao K">K-Z Tao</name></author><author><name sortKey="Ma, L" uniqKey="Ma L">L Ma</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Takagi, T" uniqKey="Takagi T">T Takagi</name></author><author><name sortKey="Naito, Y" uniqKey="Naito Y">Y Naito</name></author><author><name sortKey="Mizushima, K" uniqKey="Mizushima K">K Mizushima</name></author><author><name sortKey="Hirata, I" uniqKey="Hirata I">I Hirata</name></author><author><name sortKey="Yagi, N" uniqKey="Yagi N">N Yagi</name></author><author><name sortKey="Tomatsuri, N" uniqKey="Tomatsuri N">N Tomatsuri</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bargagli, E" uniqKey="Bargagli E">E Bargagli</name></author><author><name sortKey="Prasse, A" uniqKey="Prasse A">A. Prasse</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dyskova, T" uniqKey="Dyskova T">T Dyskova</name></author><author><name sortKey="Fillerova, R" uniqKey="Fillerova R">R Fillerova</name></author><author><name sortKey="Novosad, T" uniqKey="Novosad T">T Novosad</name></author><author><name sortKey="Kudelka, M" uniqKey="Kudelka M">M Kudelka</name></author><author><name sortKey="Zurkova, M" uniqKey="Zurkova M">M Zurkova</name></author><author><name sortKey="Gajdos, P" uniqKey="Gajdos P">P Gajdos</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Roumanie</li></country></list><tree><country name="Roumanie"><noRegion><name sortKey="Pasca, Sergiu" sort="Pasca, Sergiu" uniqKey="Pasca S" first="Sergiu" last="Pasca">Sergiu Pasca</name></noRegion><name sortKey="Jurj, Ancuta" sort="Jurj, Ancuta" uniqKey="Jurj A" first="Ancuta" last="Jurj">Ancuta Jurj</name><name sortKey="Matei, Daniela" sort="Matei, Daniela" uniqKey="Matei D" first="Daniela" last="Matei">Daniela Matei</name><name sortKey="Matei, Daniela" sort="Matei, Daniela" uniqKey="Matei D" first="Daniela" last="Matei">Daniela Matei</name><name sortKey="Petrushev, Bobe" sort="Petrushev, Bobe" uniqKey="Petrushev B" first="Bobe" last="Petrushev">Bobe Petrushev</name><name sortKey="Tomuleasa, Ciprian" sort="Tomuleasa, Ciprian" uniqKey="Tomuleasa C" first="Ciprian" last="Tomuleasa">Ciprian Tomuleasa</name><name sortKey="Tomuleasa, Ciprian" sort="Tomuleasa, Ciprian" uniqKey="Tomuleasa C" first="Ciprian" last="Tomuleasa">Ciprian Tomuleasa</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/TocilizumabV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000277 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000277 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= TocilizumabV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:7174664
|texte= MicroRNA-155 Implication in M1 Polarization and the Impact in Inflammatory Diseases
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:NONE" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a TocilizumabV1
| This area was generated with Dilib version V0.6.34. |  |